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Supplementary materials2015  2014  2013  2012  2011  2010  2009  2008

2015

Baselmans BML et al. Epigenome-Wide Association Study of Wellbeing. Twin Research and Human Genetics, Volume 18, Issue 6
Supplemental Table S1
Supplemental Table S2
Supplemental Table S3
Supplemental Table S4
Supplementary Material

Beek JHDA van et al. Heritability of liver enzyme levels estimated from genome-wide SNP data. European Journal of Human Genetics, Volume 12, Issue 9
Supplementary Materials

Bootsman F et al. Contribution of genes and unique environment to cross-sectional and longitudinal measures of subcortical volumes in bipolar disorder. European Neuropsychopharmacology, Volume 25, Issue 12

Supplementary Fig. S2
Supplementary Table S1
Supplementary Table S2
Supplementary Table S3
Supplementary Table S4

Brouwer RM et al. Longitudinal Development of Hormone Levels and Grey Matter Density in 9 and 12-Year-Old Twins. Behavior Genetics, Open Access
Supplementary .tiff 1
Supplementary .tiff 2
Supplementary .tiff 3

The Coffee and Caffeine Genetics Consortium.  Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry, Volume 20, Issue 05
Supplementary Information

Davies MN et al. Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression. PLOS ONE, Volume 10, Issue 8
Supporting Information

Day FR et al. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Psychiatry Research, Volume 47, Issue 11
Supplementary Note
Supplementary Tables 1-27

Dongen J van et al. Epigenome-Wide Association Study of Aggressive Behavior. Twin Research and Human Genetics, FirstView Article
Supplementary Material 1
Supplementary Material 2
Supplementary Material 3
Supplementary Material 4

Fall T et al. Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors. Diabetes, Published online before print
Supplementary Data

Francioli LC et al. Genome-wide patterns and properties of de novo mutations in humans. Nature Genetics, Volume 47, Issue 7
Supplementary Text and Figures

Franic S et al. Mendelian and polygenic inheritance of intelligence: A common set of causal genes? Using next-generation sequencing to examine the effects of 168 intellectual disability genes on normal-range intelligence. Intelligence, Volume 49
Supplementary Methods
Descriptions of the 168 genes

Franic S et al. Intelligence: shared genetic basis between Mendelian disorders and a polygenic trait. European Journal of Human Genetics, Advance Online Publication
Supplementary Information

Genetics of Personality Consortium.  Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry, Volume 72, Issue 7
Supplementary Online Content

Gottlieb DJ et al. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Molecular Psychiatry, Volume 20, Issue 10
Supplementary Information
Supplementary Figure 1
Supplementary Figure 2
Supplementary Figure 3

Hägg S et al. Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. International Journal of Epidemiology, Volume 44, Issue 2
Supplementary Data (link to IJE)

Hansell NK et al. Genetic Basis of a Cognitive Complexity Metric. PLOS One, Open Access
Supporting information

Hibar DP et al. Common genetic variants influence human subcortical brain structures. Nature, Volume 520
Supplementary Information
Supplementary Tables

Horikoshi M et al. Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. PLoS Genetics, Volume 11, Issue 7 
Supplementary Information

Jacobsen KK et al. Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder. Journal of Affective Disorders, Volume 172

Supplemental Data

Jansen R et al. Gene expression in major depressive disorder. Molecular Psychiatry, Advance Online Publication
Supplementary Information

Joshi PK et al. Directional dominance on stature and cognition in diverse human populations. Nature, Volume 523, Issue 7561
Supplementary Tables 1-11
Supplementary Table Legends

Kloosterman WP et al. Characteristics of de novo structural changes in the human genome. Genome Research, Published in Advance
Supplemental Material
Supplemental Table 1
Supplemental Table 2
Supplemental Table 3
Supplemental Table 4
Supplemental Table 5

Kochunov P et al. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data. NeuroImage, Volume 111
Supplementary Data

Koenis MMG et al. Development of the brain's structural network efficiency in early adolescence: A longitudinal DTI twin study. Human Brain Mapping, Volume 36, Issue 12
Supporting Information

Laurin CA et al. Genetic Analyses Benefit From Using Less Heterogeneous Phenotypes: An Illustration With the Hospital Anxiety and Depression Scale (HADS). Genetic Epidemiology, Early View
Supplementary Methods

Leeuwen EM van et al. Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications, Open Access
Supplementary Figures

Leeuwen EM van et al. Population-specific genotype imputations using minimac or IMPUTE2. Nature Protocols, Volume 10, Issue 9
Supplementary Text and Figures

Leeuwen EM van et al. Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. npj Aging and Mechanisms of Disease, Open Access
Supplementary Material

Lin BD et al. Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Genes, Volume 6, Issue 3
Supplementary Material

Locke AE et al. Genetic studies of body mass index yield new insights for obesity biology. Nature, Volume 518, Issue 7538
Supplementary Information
Supplementary Data

Luo X et al. Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Early View
Supplementary Material

Maier R et al. Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder. The American Journal of Human Genetics, Volume 96, Issue 2
Supplemental Data

Mbarek H et al. The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 168, Issue 8
Figure S1-S4 & Table S1
Supporting Information

Minica CC et al. Sandwich corrected standard errors in family-based genome-wide association studies. European Journal of Human Genetics, Volume 23, Issue 3
Supplementary Tables 1-6

Minica CC et al. Heritability, SNP- and Gene-Based Analyses of Cannabis Use Initiation and Age at Onset. Behavior Genetics, Open Access
Supplementary Material

Molenaar D et al. Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression. Behavior Genetics, Open Access
Supplementary Material on the Behavior Genetics website

Morris RW et al. Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium. BMJ Open, Volume 5, Issue 8
Supplementary Table S1 
Supplementary Table S2
Supplementary Table S3

Neijts M et al. Heritability and Temporal Stability of Ambulatory Autonomic Stress Reactivity in Unstructured 24-Hour Recordings. Psychosomatic Medicine, Volume 77, Issue 8
Supplementary Tables & Figures

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience, 18(2):199-209
Supplementary Materials on the Nature Neuroscience website

Nivard MG et al. Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years. Psychological Medicine, Volume 45, Issue 05
Supplementary Material

Nyholt DR et al. Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies. Cephalalgia, Volume 35, Issue 6
Supplementary Table
Suplementary Figures

Oh G et al. DNA Modification Study of Major Depressive Disorder: Beyond Locus-by-locus Comparisons. Biological Psychiatry, Volume 77, Issue 3
Supplementary Material

Pappa I et al. Single Nucleotide Polymorphism Heritability of Behavior Problems in Childhood: Genome-Wide Complex Trait Analysis. Journal of the American Academy of Child & Adolescent Psychiatry, Volume 54, Issue 9

Supplemental Tables S1-S6

Paternoster L et al. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics, Volume 47, Issue 12.
Supplementary Information
Supplementary Tables 5-10
Supplementary Tables 17-21

Peyrot W et al. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Molecular Psychiatry, Volume 20, Issue 6
Supplementary Materials

Power RA et al. Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nature Neuroscience, Volume 18, Issue 7
Supplementary Text and Figures
Supplementary Methods Checklist

Rahmioglu N et al. Genome-wide Enrichment Analysis between Endometriosis and Obesity-related Traits Reveals Novel Susceptibility Loci. Human Molecular Genetics, Volume 24, Issue 4
Supplementary Information

Robinson MR et al. Population genetic differentiation of height and body mass index across Europe. Nature Genetics, Volume 47, Issue 11
Supplementary Text and Figures

Shah S et al. Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. The American Journal of Human Genetics, Volume 97, Issue 1

Supplemental Data

Shungin D et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature, Volume 518, Issue 7538
Supplementary Information

Silventoinen K et al. The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits. Twin Research and Human Genetics, Volume 18, Issue 04
Supplementary Table

Sirota M et al. Effect of Genome and Environment on Metabolic and Inflammatory Profiles. PLOS One, Open Access
S1 Fig
S2 Fig
S1 Table
S2 Table

Spjuth O et al. Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research. European Journal of Human Genetics EJHG Open, Advance Online Publication
Supplementary Information S1 (xls)
Supplementary Information S2 (xls)
Supplementary Information S3 (pdf)
Supplementary Information S4 (pdf)

Surakka I et al. The impact of low-frequency and rare variants on lipid levels. Nature Genetics, Volume 47, Issue 6
Supplementary Figures, Tables and Note
Supplementary Table 9

Toulopoulou T et al. Reciprocal causation models of cognitive vs volumetric cerebral intermediate phenotypes for schizophrenia in a pan-European twin cohort. Molecular Psychiatry, Volume 20, Issue 11
Supplementary Information
Supplementary Figure S1
Supplementary Figure S2
Supplementary Table S1
Supplementary Table S2
Supplementary Table S3

Treur JL et al. Spousal resemblance for smoking: Underlying mechanismsand effects of cohort and age. Drug and Alcohol Dependence, Volume 153
Supplementary Material

Treur JL et al. Smoking during adolescence as a risk factor for attention problems. Biological Psychiatry, Volume 78, Issue 9
Supplemental Information

Valk RJP van der et al. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics, Volume 24, Issue 4
Supplementary Data
Supplementary Tables

Vink JM et al. Differential gene expression patterns between smokers and non-smokers: cause or consequence? Addiction Biology, Early View
Supplementary Data (on the AB website)

Winkler TW et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLOS Genetics, Volume 11, Issue 10
Supplementary Material on the PLOS website

Winsvold BS et al. Genetic analysis for a shared biological basis between migraine and coronary artery disease. Neurology Genetics, Volume 1
e-Methods
Figure e-1 - e-4
Table e1 - e-7
Coinvestigators

Xu T et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care, Volume 38, Issue 10
Supplementary Data

Zeeuw EL de et al. Childhood ODD and ADHD Behavior: The Effect of Classroom Sharing, Gender, Teacher Gender and Their Interactions. Behavior Genetics, Volume 45, Issue 4
Supplementary material: Table S1-S4

Zeeuw EL de et al. Meta-analysis of twin studies highlights the importance of genetic variation in primary school educational achievement. Trends in Neuroscience and Education, Volume 4, Issue 3
Supplementary Material (Word doc)

Zilhão NR et al. Genetic and Environmental Contributions to Stability in Adult Obsessive Compulsive Behavior. Twin Research and Human Genetics, Volume 18, Issue 01

Supplementary Material

Zilhão NR et al. Epigenome-Wide Association Study of Tic Disorders. Twin Research and Human Genetics, Volume 18, Issue 06
Supplementary Material

2014

Aarts E et al. A solution to dependency: using multilevel analysis to accommodate nested data. Nature Neuroscience, Volume 17, Issue 4, 2014
Supplementary simulation and analysis
Supplementary Table

Akker EB van den et al. Meta-Analysis on Blood Transcriptomic Studies Identifies Consistently Co-Expressed PPI Modules as Robust Markers of Human Ageing. Aging Cell, Volume 13, Issue 2, 2014
Supporting information FigS1 TableS1 TableS2 TableS3 TableS4 TableS5 TableS6 TableS7 DataS1

Albrecht E et al. Telomere Length in Circulating Leukocytes is Associated with Lung Function and Disease. European Respiratory Journal, Volume 43, Issue 4, 2014
Supplementary material

Baumert J et al. No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects. PLOS One, Volume 9, Issue 12, 2014
S1 fig
S2 fig
S1 Table - Basic information about studies
S2 Table - Genotype information about studies
S3 Table - Genomic inflation factor per study
S4 Table - Interaction with alcohol consumption for association with fibrinogen concentration (in g/L) among SNPs associated with circulating fibrinogen
S5 Table - Interaction with BMI for association with fibrinogen concentration (in g/L) among SNPs associated with circulating fibrinogen
S1 Funding
S1 Checklist - PRISMA checklist
S1 Methods - Additional information about study samples, fibrinogen measurements, genotyping/imputation and statistical analyses

Beek JHDA van et al. The association of alcohol intake with gamma-glutamyl transferase (GGT) levels: Evidence for correlated genetic effects. Drug and Alcohol Dependence, Volume 134, Issue 1, 2014
Supplemental Methods

Benyamin B et al. Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. Molecular Psychiatry, Volume 19, Issue 2, 2014
Supplementary Information

Berg SM van den et al. Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. Behavior Genetics, Volume 44, Issue 4, 2014
Supplementary Material

Bohlken MM et al. Genes contributing to subcortical volumes and intellectual ability implicate the thalamus. Human Brain Mapping, Early View, 2014
Supplementary Information Table 1
Supplementary Information Table 2
Supplementary Information Table 3

Brouwer RM et al. Heritability of brain volume change and its relation to intelligence. NeuroImage, Volume 100, 2014
Supplemental Table 1
Supplemental Table 2
Supplemental Figure

Brouwer RM et al. Genetic Associations Between Intelligence and Cortical Thickness Emerge at the Start of Puberty. Human Brain Mapping, Volume 35, Issue 8, 2014
Supporting Information Figure
Supporting Information Table 1
Supporting Information Table 2
Supporting Information Table 3
Supporting Information Table 4

Byrne EM et al. Applying polygenic risk scores to postpartum depression. Archives of Women's Mental Health, Volume 17, Issue 6, 2014
ESM 1 (DOCX)
ESM 2 (XLSX)
ESM 3 (PDF)

Cousminer DL et al. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics, Volume 23, Issue 16, 2014
Supplementary Data
Supplementary Table 1

Dane AD et al. Integrating Metabolomics Profiling Measurements Across Multiple Biobanks. Analytical Chemistry, Volume 86, Issue 9, 2014
Supplementary Material

Deelen J et al. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Human Molecular Genetics, Volume 23, Issue 16, 2014
Summary results & readme (files too big to host)

Deelen J et al. Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'. European Journal of Human Genetics, Volume 22, Issue 11, 2014
Supplementary Figure S1
Supplementary Table S2
Supplementary Table S3
Supplementary Figure and Tables Legend

Derks EM et al. Genetic and environmental influences on the relationship between adult ADHD symptoms and self-reported problem drinking in 6024 Dutch twins. Psychological Medicine, Volume 44, Issue 12, 2014
Supplementary Materials

Dongen J van et al. The Contribution of the Functional IL6R Polymorphism rs2228145, eQTLs and Other Genome-Wide SNPs to the Heritability of Plasma sIL-6R Levels. Behavior Genetics, Volume 44, Issue 4, 2014
Supplementary Material

Dongen J van et al. Epigenetic Variation in Monozygotic Twins: A Genome-Wide Analysis of DNA Methylation in Buccal Cells. Genes, Volume 5, Issue 2, 2014
Supplementary Material

Franic S et al. Genetic and Environmental Stability of Intelligence in Childhood and Adolescence. Twin Research and Human Genetics, Volume 17, Issue 03, 2014
Supplementary Material

Franic S et al. Three-and-a-Half-Factor Model? The Genetic and Environmental Structure of the CBCL/6–18 Internalizing Grouping. Behavior Genetics, Volume 44, Issue 3, 2014
Supplementary Table 1

GoNL/Franciolo LC. Whole-genome sequence variation, population structure and demographic history of the Dutch population. Nature Genetics, Advance Online Publication, 2014
Supplementary Text and Figures

Guigas B et al.  Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility. Diabetic Medicine, Volume 31, Issue 8, 2014
Supplementary Material

Huppertz C et al. A Twin-Sibling Study on the Relationship Between Exercise Attitudes and Exercise Behavior. Behavior Genetics, Volume 44, Issue 1, 2014
Supplementary Material

Jansen R et al. Sex differences in the human peripheral blood transcriptome. BMC Genomics, Volume 15, Issue 33, 2014
Additional files S1 S2 S3 S4 S5 S6 S7 S8 S9 S10 S11 S12
Additional info on files

Kochunov P et al. Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. NeuroImage, Volume 95, 2014
Supplementary data

Korhonen T et al. Role of Nicotine Dependence in the Association between the Dopamine Receptor Gene DRD3 and Major Depressive Disorder. PLOS One, Volume 9, Issue 6, 2014
Supporting Information

Liu CT et al. Multi-ethnic fine-mapping of 14 central adiposity loci. Human Molecular Genetics, Volume 23, Issue 17, 2014
Supplementary Document

Mathews CA et al. Partitioning the etiology of hoarding and obsessive–compulsive symptoms. Psychological Medicine, Volume 44, Issue 13, 2014
Supplementary Material

Minica CC et al. MZ twin pairs or MZ singletons in population family-based GWAS? More power in pairs. Molecular Psychiatry, Volume 19, Issue 11, 2014
Supplementary Figure

Perry JRB et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature, Advance Online Publication, 2014

Supplementary Information
Supplementary Data

Power RA et al. A recessive genetic model and runs of homozygosity in major depressive disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 165, Issue 2, 2014
Supporting Information

Swagerman S et al. Development and heritability of subcortical brain volumes at age 9 and 12. Genes, Brain and Behavior, Volume 13, Issue 8, 2014
Supporting Information

Taylor AE et al. Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium. BMJ Open, Volume 4, Issue 10, 2014
Supplementary Material

Taylor AE et al. Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers. PLOS Genetics, Volume 10, Issue 12, 2014
Text S1: Ethics approvals for individual contributing studies
Text S2: Smoking heaviness in the CARTA studies
Text S3: Data access arrangements for individual contributing studies

Treur JL et al. The Predictive Value of Smoking Expectancy and the Heritability of its Accuracy. Nicotine & Tobacco Research, Volume 16, Issue 3, 2014

Supplementary Data

Verweij KJH et al. The Association of Genotype-Based Inbreeding Coefficient with a Range of Physical and Psychological Human Traits. PLOS One, Volume 9, Issue 7, 2014

Supplemental File S1

Vink JM et al. Polygenic risk scores for smoking: predictors for alcohol and cannabis use? Addiction, Volume 109, Issue 7, 2014
Supplemental Tables

Winkler TW et al. Quality control and conduct of genome-wide association meta-analyses. Nature Protocols, Volume 9, Number 5, 2014
Supplementary figures & files

Wood AR et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics, Advance Online Publication, 2014
Supplementary Text and Figures
(Supplementary Figures 1–9, Supplementary Tables 2, 4–6, 9–12, 15 and 17–22, and Supplementary Note)
Supplementary Table 1
Supplementary Table 3
Supplementary Table 7
Supplementary Table 8
Supplementary Table 13
Supplementary Table 14
Supplementary Table 16

Wray NR et al. Research Review: Polygenic methods and their application to psychiatric traits. Journal of Child Psychology and Psychiatry, Volume 55, Issue 10, 2014
Supplementary Tables S1-S6

Wright FA et al. Heritability and genomics of gene expression in peripheral blood. Nature Genetics, Volume 46, Number 5, 2014
Supplementary Information

2013

Abdellaoui A et al. Population structure, migration, and diversifying selection in the Netherlands. European Journal of Human Genetics, Volume 21, Issue 11, 2013
Supplementary information and figures
Supplementary file (xls)

Amin N et al. Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. European Journal of Human Genetics, Volume 21, Issue 8, 2013
Supplementary material

Anttila V et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nature Genetics, Volume 45, Number 8, 2013
Supplementary information

Beek JHDA van et al. The Genetic Architecture of Liver Enzyme Levels: GGT, ALT and AST. Behavior Genetics, Volume 43, Issue 4, 2013
Supplementary Materials

Berndt SI et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics, Volume 45, Number 5, 2013
Supplementary text and figures

Boersma M et al. Growing trees in child brains: Graph theoretical analysis of EEG derived minimum spanning tree in 5 and 7 year old children reflects brain maturation. Brain Connectivity, Volume 3, Issue 1, 2013
Supplementary Data

Brandys MK et al. The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis. The World Journal of Biological Psychiatry, Volume 14, Issue 6, 2013Supplementary Material

Brant AM et al. The Nature and Nurture of High IQ: An Extended Sensitive Period for Intellectual Development. Psychological Science, Volume 24, Issue 8, 2013
Supplementary Appendix 1 and 2

Broer L et al. Meta-analysis of telomere length in 19?713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. European Journal of Human Genetics, Volume 21, Issue 10, 2013
Supplemental material

Codd V et al. Identification of seven loci affecting mean telomere length and their association with disease. Nature Genetics, Volume 45, Number 4, 2013

Supplementary text and figures

Cousminer DL et al. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, Volume 22, Issue 13, 2013
Supplementary information
Supplementary tables (xls)

Cross-Disorder Group of the Psychiatric Genomics Consortium et al. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. The Lancet, Volume 381, Issue 9875, 2013
Supplementary appendix

Culverhouse RC et al. Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC Psychiatry, 13(304)
Additional files TableS1 TableS2 TableS3

Do R et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, Volume 45, Number 11, 2013
Supplementary Information

Dongen J van et al. The heritability of metabolic syndrome traits in a large population-based sample. Journal of Lipid Research, Volume 54, Issue 10, 2013
Supplemental Methods

Draisma HHM et al. Hierarchical clustering analysis of blood plasma lipidomics profiles from mono- and dizygotic twin families. European Journal of Human Genetics, Volume 21, Issue 1, 2013
Supplemental material

Fernández-Rhodes L et al. Association of Adiposity Genetic VariantsWith Menarche Timing in 92,105 Women of European Descent. American Journal of Epidemiology, Volume 178, Issue 3, 2013
Web Appendix

Global Lipids Genetics Consortium. Discovery and refinement of loci associated with lipid levels. Nature Genetics, Volume 45, Number 11, 2013
Supplementary text and figures

Groen-Blokhuis MM et al. A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 162, Issue 5, 2013
TABLE SI
Supplementary Information

't Hart LM et al. The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. Diabetes, Volume 62, Issue 9, 2013
Supplementary data

Hek K et al. A Genome-Wide Association Study of Depressive Symptoms. Biological Psychiatry, Volume 73, Issue 7, 2013
Supplemental information

Hemani G et al. Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs. American Journal of Human Genetics, Volume 93, Issue 5, 2013
Supplemental data

Hoed M den et al. Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, Volume 45, Number 6, 2013
Supplementary information

Hong Lee S et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics, Volume 45, Number 9, 2013
Supplementary information

Hu Y-J et al. Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics. American Journal of Human Genetics, Volume 93, Issue 2, 2013
Supplemental Data

Kan KJ et al. On the Nature and Nurture of Intelligence and Specific Cognitive Abilities: The More Heritable, the More Culture Dependent. Psychological Science, Volume 24, Issue 12, 2013
Supplemental Material

Koenis MMG et al. Longitudinal Study of Hormonal and Physical Development in Young Twins. The Journal of Clinical Endocrinology & Metabolism, Volume 98, Issue 3, 2013
Supplemental Data

Loos MJHM van der et al. The Molecular Genetic Architecture of Self-Employment. PLOS One, Volume 8, Issue 4, 2013
Supporting information

Revez JA et al. A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk. Genes and Immunity, Online First, 2013
Supplementary information

Rietveld CA et al. Molecular genetics and subjective well-being. Proceedings of the National Academy of Sciences of the United States of America, Volume 110, Number 24, 2013
Supporting Information

Rietveld CA et al. GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment. Science, Volume 340, Issue 6139, 2013
Supporting Information

M. Sabater-Lleal. A Multi-Ethnic Meta-Analysis of Genome-Wide Association Studies in Over 100,000 Subjects Identifies 23 Fibrinogen-Associated Loci but no Strong Evidence of a Causal Association between Circulating Fibrinogen and Cardiovascular Disease. Circulation, Volume 128, Issue 12, 2013
Supplemental material

Schutte NM et al. Heritability of Resting State EEG Functional Connectivity Patterns. Twin Research and Human Genetics, Volume 16, Issue 05, 2013
Supplementary materials

Slof MCT et al.  Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders. Behavior Genetics, Volume 43, Issue 1, 2013
Supplementary material

Stephens SH et al. Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking. Genetic Epidemiology, Volume 37, Issue 8, 2013
Supplementary material

Velde SJ te et al.Genetic and Environmental Influences on Individual Differences in Sleep Duration During Adolescence. Twin Research and Human Genetics, Volume 16, Issue 06, 2013
Supplementary materials

Vimaleswaran KS et al. Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts. PLOS Medicine, Volume 10, Issue 2, 2013
Supporting Information

Ye K et al. Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs. Twin Research and Human Genetics, Volume 16, Issue 06, 2013
Supplementary materials

2012

Aa N van der et al. Genetic and Environmental Influences on Individual Differences in Sedentary Behavior During Adolescence. Archives of Pediatrics & Adolescent Medicine, Volume 166, Number 6, 2012
Supplementary Online Content

Abdellaoui A et al. Thought Problems from Adolescence to Adulthood: Measurement Invariance and Longitudinal Heritability. Behavior Genetics, Volume 42, Number 1, 2012
Supplementary material (Word document)

Amin N et al. Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Molecular Psychiatry, Volume 17, Issue 11, 2012
Supplemental material

Arfan Ikram M et al. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nature Genetics, Volume 44, Number 5, 2012
Supplementary information

Boraska V et al. Genome-wide meta-analysis of common variant differences between men and women. Human Molecular Genetics, Volume 21, Number 21, 2012
Supplementary data

Bradfield JP et al. A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics, Volume 44, Number 5, 2012
Supplementary information

Dongen J van et al. The continuing value of twin studies in the omics era. Nature Reviews Genetics, Volume 13, Number 9, 2012
Supplementary information

Ehli EA et al. De novo and inherited CNVs in MZ twin pairs selected for discordance and concordance on Attention Problems. European Journal of Human Genetics, Volume 20, Issue 10, 2012
Supplementary Figure 1 Supplementary Figure 2 Supplementary Figure 3 Supplementary Information (doc) Readme File (txt) Perl Script 1 (txt) Perl Script 2 (txt) Perl Script 3 (txt) Perl Script 4 (txt)

Forsberg LA et al. Age-Related Somatic Structural Changes in the Nuclear Genome of Human Blood Cells. The American Journal of Human Genetics, Volume 90, Issue 2, 2012
Figures S1-S13 and Tables S1-S8

Geels LM et al. Trends in adolescent alcohol use: Effects of age, sex and cohort on prevalence and heritability. Addiction, Volume 107, Issue 3, 2012
Table S1-S10

Haren NEM van et al. The Genetic and Environmental Determinants of the Association Between Brain Abnormalities and Schizophrenia: The Schizophrenia Twins and Relatives Consortium. Biological Psychiatry, Volume 71, Issue 10, 2012
Supplementary Information

Harst P van der et al. Seventy-five genetic loci influencing the human red blood cell. Nature, Volume 492, Issue 7429, 2012
Supplementary Information
Supplementary Table 4
Supplementary Table 5

fileadmin/user_upload/publicaties/verslaggeving/NTR-publicaties_2012/Harst_Nature-s3.xlsxHulshoff Pol HE et al. Overlapping and Segregating Structural Brain Abnormalities in Twins With Schizophrenia or Bipolar Disorder. Archives of General Psychiatry, Volume 69, Issue 4, 2012
Supplementary Online Content

Lamb DJ et al. Gene–environment interaction in teacher-rated internalizing and externalizing problem behavior in 7- to 12-year-old twins. Journal of Child Psychology and Psychiatry, Volume 53, Issue 8, 2012
Table S1

Lee PH et al. Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Translational Psychiatry, Volume 2, e184, 2012
Supplemental materials

Luciano M et al. Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 159B, Issue 6, 2012
Table S1-S3

Manning AK et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics, Volume 44, Number 6, 2012
Supplementary Note & Figures

McEachin RC et al. Convergence of genetic influences in comorbidity. BMC Bioinformatics, Volume 13, Supplement 2, 2012
Additional background

Middelberg RP et al. Loci Affecting Gamma-Glutamyl Transferase in Adults and Adolescents Show Age X SNP Iinteraction and Cardiometabolic Disease Associations. Human Molecular Genetics, Volume 21, Issue 2, 2012
Supplementary Table 1

Mook-Kanamori DO et al. Heritability Estimates of Body Size in Fetal Life and Early Childhood. PLOS One, Volume 7, Issue 7, 2012
Supporting information

Moor MHM de et al. Meta-analysis of genome-wide association studies for personality. Molecular Psychiatry, Volume 17, Issue 3, 2012
Supplementary Information (Word document)

Nürnberg ST et al. A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood, Volume 120, Issue 24, 2012
Supplemental material
Supplemental material: list of 1,285 potentially MEIS1 regulated genes

Paternoster L et al. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nature Genetics, Volume 44, Issue 2, 2012
Supplementary material

Palmer ND et al. A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans. PLoS One, Volume 7, Issue 1, 2012
Supplementary figures and tables

Supplementary table 2 (Excel file)

Raalte DH van et al. Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men. Diabetic Medicine, Volume 29, Issue 8, 2012
Supporting information

Scheet P et al. Twins, Tissue, and Time: An Assessment of SNPs and CNVs. Twin Research and Nature Genetics, Volume 15, Issue 6, 2012
Supplementary material

Scott RA et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, Volume 44, Number 9, 2012
Supplementary Note and Supplementary Figures 1–10
Supplementary tables 1-7
(Excel file)

Stein JL et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics, Volume 44, Number 5, 2012
Supplementary information

Stolk L et al. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nature Genetics, Volume 44, Issue 3, 2012
Supplementary material

Surakka I et al. A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol. Twin Research and Nature Genetics, Volume 15, Issue 6, 2012
Supplementary material

Taal HR et al. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, Volume 44, Number 5, 2012
Supplementary information
Supplementary table 1
(Excel file)
Supplementary table 2 (Excel file)

Talens RP et al. Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell, Volume 11, Issue 4, 2012
Supporting information

Vink JM et al. Sex Differences in Genetic Architecture of Complex Phenotypes?. PLoS One, Volume 7, Issue 12, 2012
Supplementary materials

Vliet-Ostaptchouk JV et al. Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp. PLoS O, Volume 7, Issue 3, 2012
Supplementary tables S1-S5

Webb BT et al. Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes. European Journal of Human Genetics, Volume 20, Issue 10, 2012
Supplementary Figure 1 (gif)
Supplementary Figure 1 (gif)
Supplementary Table (xls)
Supplementary Information (doc)

Wray NR et al. Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. Molecular Psychiatry, Volume 17, Issue 1, 2012
Supplementary file 1
Supplementary file 2

Supplementary file 3 (Excel file)

Supplementary file 4 (Excel file)

Yang J et al. FTO genotype is associated with phenotypic variability of body mass index. Nature, Volume 490, Issue 7419, 2012
Supplementary Information

2011

Bartels M et al. Adolescent Self-Report of Emotional and Behavioral Problems: Interactions of Genetic Factors with Sex and Age. Journal of the Canadian Academy of Child and Adolescent Psychiatry, Volume 20, Number 1, 2011
Supplementary tables

Chambers et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nature Genetics, Volume 43, Number 11, 2011
Supplementary information

Deelen J et al. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell, Volume 10, Issue 4, 2011
Supplementary figures
Supplementary table (Excel file)

Dehghan A et al. Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels. Circulation, Volume 123, Issue 7, 2011 
Supplemental material

Demirkan A et al. Genetic architecture of circulating lipid levels. European Journal of Human Genetics, Volume 19, Issue 7, 2011
Supplemental material

Ferreira MAR et al. Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. The Lancet, Volume 378, Number 9795, 2011
Supplementary webappendix

Gieger C et al. New gene functions in megakaryopoiesis and platelet formation. Nature, Volume 480, Issue 7376, 2011
Supplementary information

Klok MD et al. A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females. Translational Psychiatry, Volume 1, 2011 
Supplementary information

Ligthart L et al. Meta-analysis of genome-wide association for migraine in six population-based European cohorts. European Journal of Human Genetics, Volume 19, Issue 8, 2011
Supplementary table 1 (Excel file)
Supplementary table 2 (Excel file)
Supplementary table 3 (Word document)
Supplementary table 4 (Excel file)
Supplementary data

Liu Y et al. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.  Molecular Psychiatry, Volume 16, Issue 1, 2011
Supplemental material

Maugeri N et al. LPAR1 and ITGA4 Regulate Peripheral Blood Monocyte Counts. Human Mutation, Volume 32, Issue 8, 2011
Supporting information

Pergadia ML et al. A 3p26-3p25 Genetic Linkage Finding for DSM-IV Major Depression in Heavy Smoking Families. The American Journal of Psychiatry, Volume 168, Issue 8, 2011
Supplementary table 1
Supplementary table 2

Saviouk V et al. ADHD in Dutch Adults: Heritability and Linkage Study. American Journal of Medical Genetics Part B, Neuropsychiatric Genetics, Volume 156, Issue 3, 2011
Supplemental materials

Schumann G et al. Genome-wide association and genetic functional studies identify   autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Volume 108, Number 17, 2011
Supporting information
Table S01-S07

Simonis-Bik AMC et al. The heritability of beta cell function parameters in a mixed meal test design. Diabetologia, Volume 54, Issue 5, 2011
Supplemental material

Speliotes EK et al. Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits. PLoS Genetics, Volume 7, Issue 3, 2011
Supplemental material (tables S1-S10)

Strawbridge RJ et al. Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes. Diabetes, Volume 60, Issue 10, 2011
Supplementary data

Supplemental table 1

Zhu H et al. The Lin28/let-7 Axis Regulates Glucose Metabolism. Cell, Volume 147, Issue 1, 2011
Supplemental text
Supplemental table

2010

Beekman M et al. Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity. Proceedings of the National Academy of Sciences USA, Vol. 107, No. 42, 2010
Dataset S01 (Excel file)
Supporting information

Brouwer RM et al. Heritability of DTI and MTR in nine-year-old children. NeuroImage, Volume 53, Issue 3, 2010 
Supplementary content

Draisma HHM et al. Equating, or Correction for Between-Block Effects with Application to Body Fluid LC-MS and NMR Metabolomics Data Sets. Analytical Chemistry, Volume 82, No. 3, 2010
Supporting information

Eijgelsheim M et al. Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics, Volume 19, No. 19, 2010
Supplementary data
Supplemental table (Excel file)

Elks et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics, Volume 42, Number 12, 2010
Supplementary information
Supplementary table (Excel file)

Freathy RM et al for the Early Growth Genetics (EGG) Consortium. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics, Volume 42, Number 5, 2010
Supplementary table 1 (Excel file)
Supplementary table 2 (Excel file)
Supporting information

Gielen M et al. Secular trends in gestational age and birthweight in twins. Human Reproduction, Volume 25, Number 9, 2010
Supplementary tables

Haworth CMA et al. The heritability of general cognitive ability increases linearly from childhood to young adulthood. Molecular Psychiatry, Volume 15, Issue 11, 2010
Supplementary information

Heid IM et al on behalf of GIANT. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature, Volume 42, Number 11, 2010
Supplementary table 11 (Excel file)
Supplementary text and figures

Heni M et al. The Impact of Genetic Variation in the G6PC2 Gene on Insulin  Secretion Depends on Glycemia. The Journal of Clinical Endocrinology & Metabolism, Volume 95, Number 12, 2010
Supplemental data

Lango Allen et al on behalf of GIANT. Hundreds of variants clustered in genomic loci and biological pathways affect human heightNature, Volume 467, Number 7317, 2010
Supplementary information

MAGIC. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics, Volume 42, Number 2, 2010
Supplementary Text and Figures 
Supplementary Table 1 (Excel file)

Middeldorp CM et al. Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? Genes, Brain and Behavior, Volume 9, Issue 7, 2010
Supplementary figure 1

Nettleton JA et al. Interactions of Dietary Whole-Grain Intake With Fasting Glucose– and Insulin-Related Genetic Loci in Individuals of European Descent. Diabetes Care, Volume 33, Number 12, 2010
Supplement

Perlis RH et al. Genome-Wide Association Study of Suicide Attempts in Mood Disorder Patients. The American Journal of Psychiatry, Volume 167, Issue 12, 2010
Supplement

Schot van der AC et al. Genetic and environmental influences on focal brain density in bipolar disorder. Brain, Volume 133, Issue 10, 2010
Supplementary data (TIF)

Soranzo N et al. Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways. Diabetes, Volume 59, Number 12, 2010
Supporting online information
Institutional affiliations

Tables S1-S6 (Excel file)

Speliotes EK et al on behalf of GIANT. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature, Volume 42, Issue 11, 2010
Supplementary information

Talens RP et al. Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiologyThe FASEB Journal, Volume 24, Issue 9, 2010
Supplementary material

Terracciano A et al. Genome-wide association scan for five major dimensions of personality. Molecular Psychiatry, Volume 15, Issue 6, 2010
Supplementary table A (Excel file)

Supplementary table B (Excel file)

Teslovich TM et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature, Volume 466, 2010
Supplementary information

Thorgeirsson TE et al. Sequence variants at CHRNB3CHRNA6 and CYP2A6 affect smoking behavior. Nature Genetics, Volume 42, Number 5, 2010
Supplementary information

The Tobacco and Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature Genetics, Volume 42, Number 5, 2010
Supplementary information

Supplementary table (Excel file)

2009

Aulchenko YS et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nature Genetics, Volume 41, Number 1, 2009
Supplementary material

Estrada K et al. A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Human Molecular Genetics, Volume 18, No. 18, 2009
Supplementary material

Sullivan PF et al. Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Molecular Psychiatry, Volume 14, 2009
Supplementary information
Supplementary table (Excel file)

Vink JM et al. Genome-wide Association Study of Smoking Initiation and Current Smoking. The American Journal of Human Genetics, Volume 84, Issue 3, 2009
Supplemental data (Excel file)

2008

Bruder CEG et al. Phenotypically Concordant and Discordant Monozygotic Twins Display Different DNA Copy-Number-Variation Profiles. The American Journal of Human Genetics, Volume 82, 2008
Supplemental data